Cell Line Lysates
Cayman Chemical Plnt Cortex morI MorusIn 5mg
A prenylated flavonoid with diverse biological activities; inhibits UGT1A6, UGT1A7, and UGT1A8 (IC50s = 4.23, 0.98, and 3 μM, respectively); inhibits CYP3A4, CYP1A2, CYP2C9, and CYP2E1 (IC50s = 2.13, 1.27, 3.18, and 9.28 μM, respectively); inhibits A23187- and PMA-induced histamine and LTC4 production in mouse MC/9 mast cells at 4 μM; inhibits the growth of MCF-7, MDA‑MB‑231, and MDA‑MB‑453 breast cancer cells (IC50s = 13.53, 10.84, and 11.99 μM, respectively); decreases colonic tissue damage, TGF-β1 levels, and MMP-2 and MMP-9 activity in a rat model of TNBS-induced ulcerative colitis at 12.5 mg/kg per day
Cayman Chemical SpUrIdIn5O 1thIotrIpho 2.5mg
A nucleotide P2Y2 and P2Y4 receptor agonist; induces inositol phosphate accumulation in 1321N1 cells expressing the purinergic P2Y2 or P2Y4 receptors (EC50s = 14 and 81 µM, respectively)
Cayman Chemical 3Ethoy SpINSyn L 17pseud 2.5mg
An acid degradation product of 3’-ethoxy-5,6-dihydrospinosyn L; has no insecticidal activity against the tobacco budworm up to 64 ppm
Cayman Chemical ACTH18-39humn 2.5mg
A C-terminal peptide fragment of ACTH; produced via processing of ACTH in the intermediate lobe of the pituitary gland; increases cumulative food intake in fasted, but not fed, rats at 2.5 nmol/animal, intracerebroventricularly
ABclonal Technology Bcl10 Rabbit pAb
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants.
Abcam Human MKNK2 (MNK2) knockout HEK-293T cell lysate.
Human MKNK2 (MNK2) knockout HEK-293T cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human GNB1 knockout HCT116 cell lysate.
Human GNB1 knockout HCT116 cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human SMIM4 (C3orf78) knockout HeLa cell lysate.
Human SMIM4 (C3orf78) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Sino Biological Recombinant Mouse Cd1d1 & B2M Heterodimer Protein (His Tag), Endotoxin-Free
A DNA sequence encoding Mouse Cd1d1 (NP_031665.2) (Met1-Gly305) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the Mouse B2M (P01887) (Met1-Met119, A105D) constructed the plasmid 2. The two plasmids were co-expressed and the Mouse Cd1d1/B2M heterodimer was purified.
ABclonal Technology SLC44A1 Rabbit pAb
Enables choline transmembrane transporter activity. Involved in choline transport and transmembrane transport. Located in several cellular components, including cytosol, mitochondrion, and nucleoplasm. Implicated in high grade glioma.
Abcam Human PPP1R26 (KIAA0649) knockout HeLa cell lysate.
Human PPP1R26 (KIAA0649) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical HDAC8 Fluorophore 1ea
A negative modulator of mitochondrial calcium uptake selectively decreases mitochondrial over cytosolic histamine-induced calcium uptake but also decreases the mitochondrial membrane potential in HeLa cells at 10 UM binds to Micu1 in a cell-free assay (Kd 8.4 UM for the mouse protein) decreases myotube width in differentiated C2C12 skeletal muscle myoblasts in an in vitro model of myotube growth protects against ferroptosis induced by RSL3 erastin or glutamate in HT22 hippocampal cells at 2.5 UM
ABclonal Technology ARRB2 Rabbit pAb
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Abcam Human CCL20 (Macrophage Inflammatory Protein 3 alpha) knockout HeLa cell lysate.
Human CCL20 (Macrophage Inflammatory Protein 3 alpha) knockout HeLa cell lysate.
The product is subject to the following: Abcam Restricted Use Statement
ABclonal Technology EML4 Rabbit pAb
This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants.